The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2008
Filed:
Feb. 25, 2005
Ashvinikumar V. Gavai, Princeton Junction, NJ (US);
Derek J. Norris, Pennington, NJ (US);
Wen-ching Han, Newtown, PA (US);
Gregory D. Vite, Titusville, NJ (US);
Brian E. Fink, West Windsor, NJ (US);
John S. Tokarski, Princeton, NJ (US);
Ashvinikumar V. Gavai, Princeton Junction, NJ (US);
Derek J. Norris, Pennington, NJ (US);
Wen-Ching Han, Newtown, PA (US);
Gregory D. Vite, Titusville, NJ (US);
Brian E. Fink, West Windsor, NJ (US);
John S. Tokarski, Princeton, NJ (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
Disclosed are fused heterotricyclic compounds of the following formula I, or an enantiomer, diastereomer, tautomer or pharmaceutically acceptable salt thereof, wherein one of A ring or C ring is a 5-7 membered unsaturated heterocyclic ring. The disclosed compounds are useful as inhibitors of 17β-hydroxysteroid dehydrogenase 3 (17β-HSD3). Also disclosed are methods of using such compounds in the treatment of hormone sensitive diseases such as prostate cancer, and pharmaceutical compositions comprising such compounds.