The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2008
Filed:
Jun. 10, 2005
Hisashi Kawasaki, Osaka, JP;
Hiroyuki Abe, Osaka, JP;
Kazuhide Hayakawa, Osaka, JP;
Tetsuya Iida, Osaka, JP;
Shinichi Kikuchi, Osaka, JP;
Takayuki Yamaguchi, Osaka, JP;
Toyomichi Nanayama, Osaka, JP;
Hironori Kurachi, Osaka, JP;
Masahiro Tamaru, Osaka, JP;
Yoshikazu Hori, Osaka, JP;
Mitsuru Takahashi, Osaka, JP;
Takayuki Yoshida, Yokohama, JP;
Toshiyuki Sakai, Kyoto, JP;
Hisashi Kawasaki, Osaka, JP;
Hiroyuki Abe, Osaka, JP;
Kazuhide Hayakawa, Osaka, JP;
Tetsuya Iida, Osaka, JP;
Shinichi Kikuchi, Osaka, JP;
Takayuki Yamaguchi, Osaka, JP;
Toyomichi Nanayama, Osaka, JP;
Hironori Kurachi, Osaka, JP;
Masahiro Tamaru, Osaka, JP;
Yoshikazu Hori, Osaka, JP;
Mitsuru Takahashi, Osaka, JP;
Takayuki Yoshida, Yokohama, JP;
Toshiyuki Sakai, Kyoto, JP;
Japan Tobacco Inc., Tokyo, JP;
Abstract
The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.