The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2008
Filed:
Sep. 19, 2003
Haruo Sugiyama, Minoo, JP;
Masashi Gotoh, Takatsuki, JP;
Hideo Takasu, Nishinomiya, JP;
Fumio Samizo, Suita, JP;
Naoto Kusunose, Aioi, JP;
Masashi Nakatsuka, Mishima-gun, JP;
Haruo Sugiyama, Minoo, JP;
Masashi Gotoh, Takatsuki, JP;
Hideo Takasu, Nishinomiya, JP;
Fumio Samizo, Suita, JP;
Naoto Kusunose, Aioi, JP;
Masashi Nakatsuka, Mishima-gun, JP;
International Institute of Cancer Immunology, Inc., Suita-shi, JP;
Chugai Seiyaku Kabushiki Kaisha, Tokyo-to, JP;
Dainippon Sumitomo Pharma Co., Ltd., Osaka-shi, JP;
Abstract
Novel substituted type peptides of WT1 wherein the cysteine residue is substituted with a defined amino acid residue, polynucleotides encoding said peptides, cancer vaccines using those peptides or polynucleotides in vivo or in vitro, or the like are provided. Peptides which comprise an amino acid sequence of the formula: X-Y-Thr-Trp-Asn-Gln-Met-Asn-Leu (SEQ ID NO: 4) wherein X represents Ser, Ala, Abu, Arg, Lys, Orn, Cit, Leu, Phe, or Asn, and Y represents Tyr or Met, and which has an activity to induce CTLs, polynucleotides encoding said peptides, cancer vaccines which comprise those peptides or polynucleotides as an active ingredient, and the like are disclosed.