The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2008
Filed:
Apr. 25, 2006
Gregg B. Morin, Vancouver, CA;
Serge Lichtsteiner, Encinitas, CA (US);
Alain Vasserot, Carlsbad, CA (US);
Robert Adams, Redwood City, CA (US);
William H. Andrews, Reno, NV (US);
Gregg B. Morin, Vancouver, CA;
Serge Lichtsteiner, Encinitas, CA (US);
Alain Vasserot, Carlsbad, CA (US);
Robert Adams, Redwood City, CA (US);
William H. Andrews, Reno, NV (US);
Geron Corporation, Menlo Park, CA (US);
Abstract
Telomerase reverse transcriptase is part of the telomerase complex responsible for maintaining telomere length and increasing the replicative capacity of progenitor cells. Telomerase activity is turned off in mature differentiated cells, but is turned back on again in hyperplastic diseases, including many cancers. This disclosure provides regulatory elements that promote transcription in cells that express telomerase reverse transcriptase (TERT). The disclosure also provides systems using TERT promoter sequences for identifying compounds that can be used to modulate telomerase expression.