The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2008

Filed:

Jul. 29, 2005
Applicants:

Jingtai Cao, Chappaqua, NY (US);

Li-hsien Wang, Somers, NY (US);

Hsin Chieh Lin, Yorktown Heights, NY (US);

Mark W. Sleeman, Mahopac, NY (US);

Stanley J. Wiegand, Croton-on-Hudson, NY (US);

Inventors:

Jingtai Cao, Chappaqua, NY (US);

Li-Hsien Wang, Somers, NY (US);

Hsin Chieh Lin, Yorktown Heights, NY (US);

Mark W. Sleeman, Mahopac, NY (US);

Stanley J. Wiegand, Croton-on-Hudson, NY (US);

Assignee:

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); C07K 14/71 (2006.01); C12N 15/62 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods of treating diabetes in mammals, particularly humans, by blocking or inhibiting VEGF-mediated activity. A preferred inhibitor of VEGF-mediated activity is a VEGF antagonist such as the VEGF fusion protein trap of SEQ ID NO:2 capable of binding and blocking VEGF. The method of the invention may be combined with other therapies, such as with insulin therapy.


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