The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2008
Filed:
Dec. 16, 2005
Gamini Weeratunga, Brantford, CA;
Eckardt C. G. Wolf, Brantford, CA;
Nageib Mohamed, Oakville, CA;
Allan W. Rey, Brantford, CA;
Bhaskar Reddy Guntoori, Brantford, CA;
Gamini Weeratunga, Brantford, CA;
Eckardt C. G. Wolf, Brantford, CA;
Nageib Mohamed, Oakville, CA;
Allan W. Rey, Brantford, CA;
Bhaskar Reddy Guntoori, Brantford, CA;
Apotex Pharmachem Inc., Brantford, Ontario, CA;
Abstract
The present invention provides a novel and improved process for the preparation of Zonisamide and the intermediates thereof. In one aspect of the present invention, the process provides for: the preparation and isolation of a novel crystalline form of anhydrous 1,2-benzisoxazole-3-methanesulfonic acid of formula 1; the direct chlorination of the acid of formula 1 into its acid chloride of formula 2; and the in situ conversion of the intermediate acid chloride of formula 2 into Zonisamide