The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2008
Filed:
Feb. 17, 2006
Owen Brendan Wallace, Zionsville, IN (US);
Owen Brendan Wallace, Zionsville, IN (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
The present invention provides a compound of the formula (I) wherein Ris —H, —OH, —O(C-Calkyl), —OCOCH, —OCO(C-Calkyl), or —OSO(C-Calkyl); R, Rand Rare each independently —H, —OH, —O(C-Calkyl), —OCOCH, —OCO(C-Calkyl), —OSO(C-Calkyl) or halo; R4 is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidinyl, 4-morpholino, dimethylamino, diethylamino, diisopropylamino, or 1-hexamethyleneimino; n is 2 or 3; X is —S— or —HC═CH—; G is —O—, —S—, —SO—, SO, or —N(R)—, wherein Ris —H or C-Calkyl; and Y is —O—, —S—, —NH—, —NMe-, or —CH—, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions thereof, optionally in combination with estrogen and progestin; methods of inhibiting a disease associated with estrogen deprivation, and methods for inhibiting a disease associated with an aberrant physiological response to endogenous estrogen.