The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2008
Filed:
Apr. 13, 2006
Shawn Maddaford, Mississauga, CA;
Jailall Ramnauth, Brampton, CA;
Suman Rakhit, Mississauga, CA;
Joanne Patman, Mississauga, CA;
Paul Renton, Toronto, CA;
Subhash C. Annedi, Mississauga, CA;
Shawn Maddaford, Mississauga, CA;
Jailall Ramnauth, Brampton, CA;
Suman Rakhit, Mississauga, CA;
Joanne Patman, Mississauga, CA;
Paul Renton, Toronto, CA;
Subhash C. Annedi, Mississauga, CA;
NeurAxon, Inc., Toronto, Ontario, CA;
Abstract
The present invention features inhibitors of nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing conditions such as, for example, stroke, reperfusion injury, neurodegeneration, head trauma, CABG, migraine headache with and without aura, migraine with allodynia, central post-stroke pain (CPSP), neuropathic pain, morphine/opioid induced tolerance and hyperalgesia.