The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2008
Filed:
May. 24, 2005
Nicholas M. Dean, Olivenhain, CA (US);
Kenneth W. Dobie, Del Mar, CA (US);
Erich Koller, Carlsbad, CA (US);
Nicholas M. Dean, Olivenhain, CA (US);
Kenneth W. Dobie, Del Mar, CA (US);
Erich Koller, Carlsbad, CA (US);
Isis Pharmaceuticals, Inc., Carlsbad, CA (US);
Abstract
Compounds, compositions and methods are provided for modulating the expression of Aurora B. The compositions comprise oligonucleotides, targeted to nucleic acid encoding Aurora B. Methods of using these compounds for modulation of Aurora B expression and for diagnosis and treatment of diseases and conditions associated with expression of Aurora B are provided. Also provided are methods of using these compounds to modulate the growth of cancer cells, including p53-deficient cancer cells.