The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2008
Filed:
Jun. 30, 2005
Klaus Paulini, Maintal, DE;
Matthias Gerlach, Brachttal, DE;
Eckhard Günther, Maintal, DE;
Emmanuel Polymeropoulos, Franfurt am Main, DE;
Silke Baasner, Schöneck, DE;
Peter Schmidt, Schöneck, DE;
Ronald Kühne, Berlin, DE;
Arvid Söderhäll, Spanga, SE;
Klaus Paulini, Maintal, DE;
Matthias Gerlach, Brachttal, DE;
Eckhard Günther, Maintal, DE;
Emmanuel Polymeropoulos, Franfurt am Main, DE;
Silke Baasner, Schöneck, DE;
Peter Schmidt, Schöneck, DE;
Ronald Kühne, Berlin, DE;
Arvid Söderhäll, Spanga, SE;
AE Zentaris GmbH, Frankfurt, DE;
Abstract
The present invention provides novel tetrahydrocarbazole derivatives which have improved properties and which can be employed as inhibitors of GPCRs. This results in the possibility of using the novel compounds to treat pathological conditions whose severity depends on the pathobiochemical effect of GPCRs. The compounds of the invention act in particular via an antagonistic inhibition of the LHRH receptor. The invention further provides medicaments which comprise one or more of the novel compounds as active ingredient. The medicaments are suitable in particular to be employed in an oral dosage form for a mammal, in particular a human.