The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2008
Filed:
Feb. 01, 2006
Magdalena Eisinger, Demarest, NJ (US);
Louis J. Fitzpatrick, Souderton, PA (US);
Daniel H. Lee, Sudbury, MA (US);
Kevin Pan, Phoenixville, PA (US);
Carlos Plata-salaman, Ambler, PA (US);
Allen B. Reitz, Lansdale, PA (US);
Virginia L. Smith-swintosky, Hatfield, PA (US);
Boyu Zhao, Lansdale, PA (US);
Magdalena Eisinger, Demarest, NJ (US);
Louis J. Fitzpatrick, Souderton, PA (US);
Daniel H. Lee, Sudbury, MA (US);
Kevin Pan, Phoenixville, PA (US);
Carlos Plata-Salaman, Ambler, PA (US);
Allen B. Reitz, Lansdale, PA (US);
Virginia L. Smith-Swintosky, Hatfield, PA (US);
Boyu Zhao, Lansdale, PA (US);
Ortho-McNeil Pharmaceutical, Inc., Raritan, NJ (US);
Abstract
The present invention is directed to novel 1,2,4-thiadiazole derivatives useful as agonists or antagonists of the melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatment of metabolic, CNS and dermatological disorders such as obesity, impaired oral glucose tolerance, elevated blood glucose levels, type II diabetes, Syndrome X, diabetic retinopathy, spinal cord injury, nerve injury, acute neurodegenerative disorders, chronic neurodegenerative disorders, plexopathies, male erectile dysfunction, dry eyes, acne, dry skin, aged skin, seborrheic dermatitis, rosacea, excessive ear wax, meibomian gland disorder, pseudofolliculitis, yeast infections, dandruff, hidradenitis suppurativa, ocular rosacea and eccrine gland disorder.