The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2008
Filed:
Sep. 05, 2002
Applicants:
David Kenneth Dean, Harlow, GB;
Andrew Kenneth Takle, Harlow, GB;
David Matthew Wilson, Harlow, GB;
Inventors:
Assignee:
SmithKline Beecham p.l.c., Brentford, Middlesex, GB;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/4545 (2006.01); A61K 31/443 (2006.01); C07D 413/14 (2006.01); C07D 211/32 (2006.01); C07D 405/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
Compounds and their use as pharmaceuticals particularly as Raf kinase inhibitors for the treatment of neurotraumatic diseases, cancer, chronic neurodegeneration, pain, migraine and cardiac hypertrophy. Wherein X is O, CHCO, S or NH, or the moiety X—Ris hydrogen; Yand Yindependently represent CH or N; Ar is a mono- or fused bicyclic aromatic or heteroaromatic group which may be optionally substituted; one of Xand Xis selected from O, S or NRand the other is CH, wherein Ris hydrogen, Calkyl, aryl or arylCalkyl.