The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 2008

Filed:

Mar. 03, 2003
Applicants:

Toshiki Murata, Nara-ken, JP;

Sachiko Sakakibara, Aichi-ken, JP;

Takashi Yoshino, Nara-ken, JP;

Hiroki Sato, Nara-ken, JP;

Yuji Koriyama, Nara-ken, JP;

Noriko Nunami, Nara-ken, JP;

Megumi Yamauchi, Nara-ken, JP;

Keiko Fukushima, Nara-ken, JP;

Rolf Grosser, Leverkusen, DE;

Kinji Fuchikami, Kyoto-fu, JP;

Kevin Bacon, Hyogo, JP;

Timothy Lowinger, Guilford, CT (US);

Inventors:

Toshiki Murata, Nara-ken, JP;

Sachiko Sakakibara, Aichi-ken, JP;

Takashi Yoshino, Nara-ken, JP;

Hiroki Sato, Nara-ken, JP;

Yuji Koriyama, Nara-ken, JP;

Noriko Nunami, Nara-ken, JP;

Megumi Yamauchi, Nara-ken, JP;

Keiko Fukushima, Nara-ken, JP;

Rolf Grosser, Leverkusen, DE;

Kinji Fuchikami, Kyoto-fu, JP;

Kevin Bacon, Hyogo, JP;

Timothy Lowinger, Guilford, CT (US);

Assignee:

Bayer HealthCare AG, Leverkusen, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); A61K 31/5365 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

An optically active (−)-7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-5-[(3S)-3-piperidinyl]-1,4-dihydro-2H-pyrido[2,3-d][1,3]oxazin-2-one of the formula (I) or salt thereof. The compound has an excellent anti-inflammatory activity, and other biological activity


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