The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 2008

Filed:

Jun. 27, 2005
Applicants:

Zice Fu, Foster City, CA (US);

Michael G. Johnson, San Francisco, CA (US);

An-rong LI, South San Francisco, CA (US);

Andrew P. Marcus, Berkeley, CA (US);

Julio C. Medina, San Carlos, CA (US);

Philippe Bergeron, San Mateo, CA (US);

Xiaoqi Chen, Palo Alto, CA (US);

Xiaohui Du, Foster City, CA (US);

Jeffrey Deignan, San Francisco, CA (US);

Jason A. Duquette, Millbrae, CA (US);

Darin Gustin, Half Moon Bay, CA (US);

Jeffrey T. Mihalic, San Francisco, CA (US);

Jiwen Liu, Foster City, CA (US);

Inventors:

Zice Fu, Foster City, CA (US);

Michael G. Johnson, San Francisco, CA (US);

An-Rong Li, South San Francisco, CA (US);

Andrew P. Marcus, Berkeley, CA (US);

Julio C. Medina, San Carlos, CA (US);

Philippe Bergeron, San Mateo, CA (US);

Xiaoqi Chen, Palo Alto, CA (US);

Xiaohui Du, Foster City, CA (US);

Jeffrey Deignan, San Francisco, CA (US);

Jason A. Duquette, Millbrae, CA (US);

Darin Gustin, Half Moon Bay, CA (US);

Jeffrey T. Mihalic, San Francisco, CA (US);

Jiwen Liu, Foster City, CA (US);

Assignee:

AMGEN SF, LLC, South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 239/72 (2006.01); A61K 31/513 (2006.01); A61K 31/519 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds are provided having the formula: wherein variables A, A, A, A, R, R, R, R, Q and L are as described herein. The subject compounds are useful for treatment of inflammatory and immune conditions and diseases. Compositions and methods of treatment using the subject compounds are also provided. For example, the subject methods are useful for treatment of inflammatory and immune disorders and disease such as multiple sclerosis, rheumatoid arthritis, psoriasis, and inflammatory bowel disease.


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