The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2008
Filed:
Apr. 22, 2004
Nico Braeuer, Jena, DE;
Olaf Peters, Tabarz, DE;
Alexander Hillisch, Velbert, DE;
Rolf Bohlmann, Berlin, DE;
Margit Richter, Jena, DE;
Hans-peter Muhn, Berlin, DE;
Nico Braeuer, Jena, DE;
Olaf Peters, Tabarz, DE;
Alexander Hillisch, Velbert, DE;
Rolf Bohlmann, Berlin, DE;
Margit Richter, Jena, DE;
Hans-Peter Muhn, Berlin, DE;
Schering A.G., Berlin, DE;
Abstract
This invention relates to 8β-vinyl-11β-(ω-substituted)alkyl-estra-1,3,5(10)-trienes of general formula I with ERβ-antagonistic activity, process for their production, their intermediate products, pharmaceutical preparations that contain the compounds according to the invention, as well as their use for the production of pharmaceutical agents. The new compounds can be used for contraception in men and women without influencing other estrogen-sensitive organs such as the uterus or the liver. They are also suitable for treating benign or malignant proliferative diseases of the ovary, such as ovarian cancer and granulosa cell tumors.