The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2008
Filed:
Jul. 15, 2002
Ulrike Kroll, Münster, DE;
Willi Kuper, Gross-Rohrheim, DE;
Ulrike Kroll, Münster, DE;
Willi Kuper, Gross-Rohrheim, DE;
Steigerwald Arzneimittelwerk GmbH, Darmstadt, DE;
Abstract
In a method for the production of tablets from plant extracts such as St. John's wort extract with an extract content of 80%, the extract treated on a conveyor dryer is compacted after adding 1% of silicon dioxide, and a granulate with a defined particle size distribution and therefore a defined surface area is produced from the compactate. To achieve a high rate of decomposition and active agent release with a low adjuvant content and high extract content, a combination of blasting agents including sodium hydrogencarbonate and two other, lower-dosed blasting agents such as croscarmellose sodium and sodium carboxymethyl starch—among other adjuvants—is added. The method results in a tablet suitable for oral administration containing 900 mg of St. John's wort extract.