The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 2008

Filed:

Feb. 11, 2002
Applicants:

Feng-jing Chen, Salt Lake City, UT (US);

Srinivasan Venkateshwaran, Salt Lake City, UT (US);

Steven L. Krill, Park City, UT (US);

Mahesh V. Patel, Salt Lake City, UT (US);

Inventors:

Feng-Jing Chen, Salt Lake City, UT (US);

Srinivasan Venkateshwaran, Salt Lake City, UT (US);

Steven L. Krill, Park City, UT (US);

Mahesh V. Patel, Salt Lake City, UT (US);

Assignee:

Lipocine, Inc., Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/48 (2006.01); A61K 9/40 (2006.01); A61K 9/14 (2006.01); A61K 9/66 (2006.01); A61K 9/52 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention pertains to pharmaceutical formulations and systems for delivery of active agents, wherein a first fraction of an active agent is suspended in a vehicle and a second fraction of active agent is solubilized in the vehicle, with the suspended fraction representing about 5 wt. % to about 80 wt. % of the active agent and the second fraction representing about 20 wt. % to about 95 wt. % of the active agent. One or more additional active agents, which may be fully solubilized, partially solubilized, or suspended, may also be present. The first and second fractions of the active agent may or may not have different release profiles. Generally, a significant fraction of the solubilized drug will release rapidly, providing for rapid onset, while the suspended drug may be formulated for delayed and/or sustained release.


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