The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 2008

Filed:

Aug. 11, 2004
Applicants:

Patrick W. K. Lee, Halifax, CA;

James Strong, Calgary, CA;

Matthew C. Coffey, Calgary, CA;

Inventors:

Patrick W. K. Lee, Halifax, CA;

James Strong, Calgary, CA;

Matthew C. Coffey, Calgary, CA;

Assignee:

Oncolytics Biotech Inc., Calgary, Alberta, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/01 (2006.01); A61K 48/00 (2006.01); C12N 7/02 (2006.01); C12N 15/88 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for treating proliferative disorders, by administering reovirus to a Ras-mediated proliferative disorder, are disclosed. The reovirus is administered so that it ultimately directly contacts ras-mediated proliferating cells. Proliferative disorders include but are not limited to neoplasms. Human reovirus, non-human mammalian reovirus, and/or avian reovirus can be used. If the reovirus is human reovirus, serotype 1 (e.g., strain Lang), serotype 2 (e.g., strain Jones), serotype 3 (e.g., strain Dearing or strain Abney), as well as other serotypes or strains of reovirus can be used. Combinations of more than one type and/or strain of reovirus can be used, as can reovirus from different species of animal. Either solid neoplasms or hematopoietic neoplasms can be treated.


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