The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2008
Filed:
Jan. 29, 2005
Danica Ramljak, McLean, VA (US);
Leo J. Romanczyk, Jr., Hackettstown, NJ (US);
Robert B. Dickson, Kensington, MD (US);
Danica Ramljak, McLean, VA (US);
Leo J. Romanczyk, Jr., Hackettstown, NJ (US);
Robert B. Dickson, Kensington, MD (US);
Mars, Incorporated, McLean, VA (US);
Abstract
This invention relates to methods of inducing dephosphorylation of a hyperphosphorylated cell cycle regulatory protein in a tumor cell in which hyperphosphorylation of said protein contributed to cell transformation, the method comprising contacting the tumor cell with a procyanidin oligomer of five monomeric units connected via a C-4→C-8 linkage. Examples of such compounds are [EC-(4β→8)]-EC, and [EC-(4β→8)]-EC-(4β→8)-C, wherein EC is epicatcchin and C is catechin.