The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2008
Filed:
Dec. 06, 2005
Roelof Van Hes, Weesp, NL;
Pieter Smid, Weesp, NL;
Cornelis G. Kruse, Weesp, NL;
Martinus Th. M. Tulp, Weesp, NL;
Roelof van Hes, Weesp, NL;
Pieter Smid, Weesp, NL;
Cornelis G. Kruse, Weesp, NL;
Martinus Th. M. Tulp, Weesp, NL;
Solvay Pharmaceuticals B.V., Weesp, NL;
Abstract
The present invention relates to a group of novel tetrahydropyridin-4-yl indoles with a dual mode of action: serotonin reuptake inhibition and affinity for dopamine-Dreceptors, to methods for the preparation of these compounds and to novel intermediates useful for the synthesis of said tetrahydropyridin-4-yl indoles. The invention also relates to the use of a compound disclosed herein for the manufacture of a medicament giving a beneficial effect. The invention relates to novel tetrahydropyridin-4-yl indoles of the formula. and tautomers, stereoisomers, prodrugs, N-oxides, pharmacologically acceptable salts, hydrates and solvates thereof,wherein: