The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2008

Filed:

Sep. 21, 2004
Applicants:

Saleem Ahmad, Wall, NJ (US);

Jeffrey A. Robl, Newtown, PA (US);

Khehyong Ngu, Pennington, NJ (US);

Inventors:

Saleem Ahmad, Wall, NJ (US);

Jeffrey A. Robl, Newtown, PA (US);

Khehyong Ngu, Pennington, NJ (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/42 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); A61K 31/506 (2006.01); A61P 3/06 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds are provided having the following structure which are HMG CoA reductase inhibitors and thus are active in inhibiting cholesterol biosynthesis, modulating blood serum lipids, for example, lowering LDL cholesterol and/or increasing HDL cholesterol, and treating hyperlipidemia, dyslipidemia, hormone replacement therapy, hypercholsterolemia, hypertriglyceridemia and atherosclerosis as well as Alzheimer's disease and osteoporosis wherein X is N or CR;and pharmaceutically acceptable salts thereof, wherein Rto Rare as defined herein. A method for treating the above diseases employing the above compounds is also provided.


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