The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2008
Filed:
Apr. 22, 2003
Nigel C. Phillips, Point-Claire, CA;
Mario C. Filion, Laval, CA;
Nigel C. Phillips, Point-Claire, CA;
Mario C. Filion, Laval, CA;
Bioniche Life Sciences Inc., Belleville, Ontario, CA;
Abstract
The present invention relates to 3'-OH, 5′-OH polynucleotide sequence compositions and methods for activating an immune response in an individual, and more preferably, for activating antigen presenting cells in the individual. In one embodiment, the antigen presenting cell is a dendritic cell. The present invention also includes compositions and methods for activating dendritic cells in vitro. These dendritic cells may then be administered to an individual. Preferred 3′-OH, 5′-OH polynucleotide sequences comprise six bases wherein at least 50% of the bases are guanine and the 5′ base is guanine. The compositions may comprise a phosphodiester or phosphorothioate backbone.