The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2008

Filed:

Jan. 04, 2006
Applicants:

Yun-ming Wang, Kaohsiung, TW;

Wei-hsan Chao, Kaohsiung, TW;

Gin-chung Liu, Kaohsiung, TW;

Jui-sheng Hsu, Kaohsiung, TW;

Inventors:

Yun-Ming Wang, Kaohsiung, TW;

Wei-Hsan Chao, Kaohsiung, TW;

Gin-Chung Liu, Kaohsiung, TW;

Jui-Sheng Hsu, Kaohsiung, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2006.01); C07K 7/04 (2006.01); A61K 38/00 (2006.01); A61K 38/02 (2006.01); C07K 2/00 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides a novel probe, which contains a prostate peptide substrate. The probe can be used as a prostate diagnostic agent for optical imaging. An 11 amino acid peptide substrate is synthesized for specific prostate-specific antigen (PSA). This protected graft copolymer (PGC) consists of a poly-L-lysine (PL) backbone and methoxypoly(ethylene glycol) (MPEG). Two terminals of peptide substrate are bound to poly-L-lysine and Cy5.5 fluorochrome. This probe will be used as a NIR (near-infrared fluorescence) probe for optical imaging.


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