Five-membered heterocyclic compounds

Abstract

The present invention provides a compound represented by the formula: wherein Ris an optionally substituted 5-membered heterocyclic group; X, Y and V are the same or different and each is a bond, an oxygen atom, a sulfur atom and the like; Q is a divalent hydrocarbon group having 1 to 20 carbon atoms; ring A is an aromatic ring optionally further having 1 to 3 substituents; Z is —(CH)-Z- or -Z-(CH)— (n is an integer of 0 to 8, Zis a bond, an oxygen atom, a sulfur atom and the like); ring B is a nitrogen-containing heterocycle optionally further having 1 to 3 substituents; W is a bond or a divalent hydrocarbon group having 1 to 20 carbon atoms; Ris a hydrogen atom, a cyano group, —PO(OR)(OR) (Rand Rare the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, and Rand Rare optionally bonded to form an optionally substituted ring) and the like, or a salt thereof, which has a superior adipose tissue weight decreasing action, a hypoglycemic action and a hypolipidemic action, and which is useful as an agent for the prophylaxis or treatment of obesity, diabetes mellitus, hyperlipidemia, impaired glucose tolerance, hypertension and the like.