The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 06, 2008

Filed:

Nov. 01, 2002
Applicants:

Russell Bialecki, Wilmington, DE (US);

Cathy Dantzman, Wilmington, DE (US);

Keith Herzog, Wilmington, DE (US);

Inventors:

Russell Bialecki, Wilmington, DE (US);

Cathy Dantzman, Wilmington, DE (US);

Keith Herzog, Wilmington, DE (US);

Assignee:

AstraZeneca AB, Sodertalje, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4545 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

NK2R binding compounds in accord with structural diagram I useful for the treatment or prevention of OAB or UI in mammals, particularly humans are disclosed: wherein in said compounds D, A, R, Rand Rare as defined in the specification. Pharmaceutically-advantageous salts of the compounds, methods of use of the compounds, either alone or in combination with other pharmacological agents, and pharmaceutical compositions useful in practicing the methods of the invention are also disclosed.


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