The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 06, 2008

Filed:

Nov. 19, 2004
Applicants:

Rustum S. Boyce, San Francisco, CA (US);

Jason D. Speake, Cary, NC (US);

James Phillips, Bay Village, OH (US);

Inventors:

Rustum S. Boyce, San Francisco, CA (US);

Jason D. Speake, Cary, NC (US);

James Phillips, Bay Village, OH (US);

Assignees:

Chiron Corporation, Emeryville, CA (US);

Glaxo SmithKline, Research Triangle Park, NC (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); C07D 239/72 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

A variety of small molecule, guanidine-containing molecules capable of acting as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases when administered to subjects. The compounds have the formula IA and IB. IA and IB have the following structures where Z has the formula shown below and the rest of the variables are defined herein


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