The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2008
Filed:
Jun. 14, 2006
Bilha Fischer, Shoham, IL;
Victoria Nahum, Rishon-le-Zion, IL;
Bilha Fischer, Shoham, IL;
Victoria Nahum, Rishon-le-Zion, IL;
BAR - ILAN University, Ramat Gan, IL;
Abstract
The present invention provides dinucleoside boranophosphate derivatives of the general formula I: wherein X and X' each independently is an unsubstituted or substituted purine or pyrimidine residue; Y and Y′ each independently is H or OH; Zto Zeach independently is Oor BH, but excluding the compounds wherein Zto Zare each O; Wto Weach independently is O, CH, NH or C(Halogen); n and n′ each independently is 0 or 1; m is 3, 4 or 5; and Mrepresents a pharmaceutically acceptable cation, and to pharmaceutical compositions thereof. These dinucleoside boranophosphates are useful for prevention or treatment of diseases or disorders modulated by P2Y receptors such as type 2 diabetes, cystic fibrosis and cancer.