The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7368422 B1

PDF
Full Text
Expired
Date of Patent:
May. 06, 2008

Filed:

Feb. 24, 2006
Applicants:

Yaohui Lei, Hebei, CN;

Yu Bai, Hebei, CN;

Daniel Chu, Santa Clara, CA (US);

Zhi-jie NI, Fremont, CA (US);

John Jian-xin Wang, Oakland, CA (US);

Inventors:

Yaohui Lei, Hebei, CN;

Yu Bai, Hebei, CN;

Daniel Chu, Santa Clara, CA (US);

Zhi-Jie Ni, Fremont, CA (US);

John Jian-Xin Wang, Oakland, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/02 (2006.01); A61K 38/12 (2006.01); A61K 31/70 (2006.01); C07K 7/64 (2006.01); C07K 9/00 (2006.01); C07K 5/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

Semi-synthetic glycopeptides that have antibacterial activity are based on modifications of a rearranged vancomycin or desmethyl-vancomycin scaffold, in particular, alkylation or acylation of the amino substituent on the amino-substituted sugar moiety on this scaffold with certain acyl groups; and/or conversion of the acid moiety on the macrocyclic ring of this scaffolds to certain substituted amides. Also provided are methods for synthesis of the compounds, pharmaceutical compositions containing the compounds, and methods of use of the compounds for the treatment and/or prophylaxis of diseases, especially bacterial infections.


Find Patent Forward Citations

Lei, Yaohui. (2008). Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity (U.S. Patent No. 7368422). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7368422

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