The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2008
Filed:
Feb. 01, 2005
Kap-soo Noh, Seoul, KR;
Yeong-chul Kim, Seoul, KR;
Jae-yong Park, Seoul, KR;
Dai-chul Kim, Kyungki-do, KR;
Jin-ho Lee, Kyungki-do, KR;
Seung-han OK, Busan, KR;
Kap-Soo Noh, Seoul, KR;
Yeong-Chul Kim, Seoul, KR;
Jae-Yong Park, Seoul, KR;
Dai-Chul Kim, Kyungki-do, KR;
Jin-Ho Lee, Kyungki-do, KR;
Seung-Han Ok, Busan, KR;
CJ Corporation, , KR;
Abstract
A method for producing L-threonine using a microorganism is provided. In the method, additional one or more copies of each of the phosphoenolpyruvate carboxylase (ppc) gene and the threonine operon are integrated into a particular site of the chromosomal DNA of a microorganism, while its inherent ppc gene and threonine operon remain. Accordingly, two or more ppc genes and threonine operons are included in the chromosomal DNA of the microorganism to thereby enhance the expression of the ppc gene encoding an enzyme to convert phosphoenolpyruvate to a threonine biosynthesis precursor, oxaloacetete, and the genes encoding enzymes involved in the synthetic pathway of threonine from oxaloacetate, including thrA (aspartokinasel-homoserine dehydrogenase), thrB (homoserine kinase), and thrC (threonine synthase), thereby markedly increasing L-threonine productivity.