The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 06, 2008

Filed:

Feb. 03, 2004
Applicants:

Yoshiki Katayama, Fukuoka, JP;

Hiroaki Shimokawa, Fukuoka, JP;

Tatsuhiro Yamamoto, Fukuoka, JP;

Inventors:

Yoshiki Katayama, Fukuoka, JP;

Hiroaki Shimokawa, Fukuoka, JP;

Tatsuhiro Yamamoto, Fukuoka, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/055 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

An MRI contrast agent enables direct detection and imaging of exfoliated vascular endothelial sites. The MRI contrast agent includes an imaging unit which contains an unpaired electron-carrying atom and/or molecule and is capable of amplifying or reducing MRI signals, and a detection unit which is bonded to the imaging unit and is capable of selectively recognizing exfoliated vascular endothelial sites and binding thereto. The detection unit is exemplified by one having a chemical structure expressed by the following formula (I), wherein at least one of R-Ris, for example, a sulfonic acid group, and X is, for example, a phenyl group which may be substituted:


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