The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2008
Filed:
Dec. 23, 2002
Sabine Mueller, San Francisco, CA (US);
Mirella Gonzalez-zulueta, Pacifica, CA (US);
Erik Foehr, Novato, CA (US);
Daniel J. Chin, Foster City, CA (US);
Sabine Mueller, San Francisco, CA (US);
Mirella Gonzalez-Zulueta, Pacifica, CA (US);
Erik Foehr, Novato, CA (US);
Daniel J. Chin, Foster City, CA (US);
Medarex, Inc., Princeton, NJ (US);
Abstract
The present invention relates to the use of a protein that is differentially expressed in primary brain tumor tissues, as compared to normal brain tissues, as a biomolecular target for tumor treatment therapies. The protein is also expressed in tissues from adenocarcinoma, non-melanoma, and renal carcinoma cells. Immunotherapeutic and immunoimaging agents that specifically bind to an identified brain tumor target protein are provided. The present invention also provides compounds and pharmaceutically acceptable compositions for administration in the methods of the invention.