The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2008

Filed:

Oct. 11, 2004
Applicants:

Alain Burgos, Les Ponts-de-Cé, FR;

Blandine Bertrand, Angrie, FR;

Stéphane Frein, Saint-Aubin-de-Luigné, FR;

Jean-françois Pluvie, Angers, FR;

Sonia Roussiasse, Champigne, FR;

Inventors:

Alain Burgos, Les Ponts-de-Cé, FR;

Blandine Bertrand, Angrie, FR;

Stéphane Frein, Saint-Aubin-de-Luigné, FR;

Jean-François Pluvie, Angers, FR;

Sonia Roussiasse, Champigne, FR;

Assignee:

ZaCh System S.p.A., Milan, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 5/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

A process for the in situ preparation of chiral compounds derived from oxazaborolidine-borane complexes, wherein a metal borohydride, a Lewis base and an inorganic acid ester are brought together and an optically active amino alcohol and optionally a halide are then added. The compound obtained is a complex that is useful as a catalyst in asymmetric reduction reactions. The reaction is performed by adding the substance to be reduced, particularly prochiral ketones or ether oximes, in order to synthesize chiral alcohols or chiral amines.


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