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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7365196 B1

PDFFull Text
Date of Patent:
Apr. 29, 2008

Filed:

Mar. 15, 2001

Sulphonamido-substituted bridged bicycloalkyl derivatives

Applicants:

Patrice Charles Belanger, Dollard-des-Ormeaux, CA;

Ian James Collins, Ware, GB;

Joanne Claire Hannam, Stanstead, GB;

Timothy Harrison, Great Dunmow, GB;

Stephen John Lewis, East Barnet, GB;

Andrew Madin, Sawbridgeworth, GB;

Edward Giles Mciver, Bishops Stortford, GB;

Alan John Nadin, Sawbridgeworth, GB;

Joseph George Neduvelil, East Barnet, GB;

Mark Steven Shearman, Bishops Stortford, GB;

Adrian Leonard Smith, Simi Valley, CA (US);

Timothy Jason Sparey, London, GB;

Graeme Irvine Stevenson, Saffron Walden, GB;

Martin Richard Teall, Bishops Stortford, GB;

Inventors:

Patrice Charles Belanger, Dollard-des-Ormeaux, CA;

Ian James Collins, Ware, GB;

Joanne Claire Hannam, Stanstead, GB;

Timothy Harrison, Great Dunmow, GB;

Stephen John Lewis, East Barnet, GB;

Andrew Madin, Sawbridgeworth, GB;

Edward Giles McIver, Bishops Stortford, GB;

Alan John Nadin, Sawbridgeworth, GB;

Joseph George Neduvelil, East Barnet, GB;

Mark Steven Shearman, Bishops Stortford, GB;

Adrian Leonard Smith, Simi Valley, CA (US);

Timothy Jason Sparey, London, GB;

Graeme Irvine Stevenson, Saffron Walden, GB;

Martin Richard Teall, Bishops Stortford, GB;

Assignees:

Merck Sharp & Dohme Ltd., Hoddesdom, Hertfordshire, GB;

Merck Frosst Canada & Co., Kirkland, Quebec, CA;

Attorneys:

William Krovatin

John C. Todaro

Primary Examiner:

Mark L Berch

Int. Cl.
CPC ...
C07D 413/14 (2006.01); C07D 413/12 (2006.01); C07D 213/71 (2006.01); C07D 213/52 (2006.01); C07D 333/34 (2006.01); C07D 409/14 (2006.01); C07D 409/12 (2006.01); C07D 249/12 (2006.01); C07D 233/84 (2006.01); C07D 207/48 (2006.01); C07D 277/16 (2006.01); C07D 307/64 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
Abstract

A class of compounds is disclosed, comprising sulphonamido-substituted bridged bicycloalkyl structures. The compounds are inhibitors of gamma-secretase, and hence are useful in the treatment of and/or prevention of Alzheimer's disease.

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