The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2008
Filed:
Aug. 07, 2003
Marino Artico, Rome, IT;
Paolo Lacolla, Cagliari, IT;
Romano Silvestri, Rome, IT;
Adel Moussa, Burlington, MA (US);
Jean-pierre Sommadossi, Cambridge, MA (US);
Richard Storer, Folkestone, GB;
Marino Artico, Rome, IT;
Paolo LaColla, Cagliari, IT;
Romano Silvestri, Rome, IT;
Adel Moussa, Burlington, MA (US);
Jean-Pierre Sommadossi, Cambridge, MA (US);
Richard Storer, Folkestone, GB;
Idenix Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
This invention is in the area of phenylindoles that are useful for the treatment of HIV infection, and, in particular, phenylindoles that exhibit significant activity against resistant strains of HIV. The phenylindoles have at least two substituents other than hydrogen on the benzo ring of the indole function, preferably at the 4' and 5′, 5′ and 6′ or the 5′ and 7′ positions, optionally in combination with disubstitution at positions 3″ and 5″ on the phenyl ring of the compound, and carboxamide containing moieties at position-2 on the indole group of the compound. Methyl is a preferred group for substitution on the phenyl ring. Preferred substituents for the benzo ring of the indole function include but are not limited to chlorine, fluorine, bromine, iodine, CF, methoxy, CN, and NO.