The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2008

Filed:

Aug. 06, 2002
Applicants:

David E. Lowery, Portage, MI (US);

Valdin G. Smith, Kalamazoo, MI (US);

Teresa M. Kubiak, Richland, MI (US);

Martha J. Larsen, Kalamazoo, MI (US);

Inventors:

David E. Lowery, Portage, MI (US);

Valdin G. Smith, Kalamazoo, MI (US);

Teresa M. Kubiak, Richland, MI (US);

Martha J. Larsen, Kalamazoo, MI (US);

Assignee:

Pharmacia & Upjohn Company, Kalamazoo, MI (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C12N 5/06 (2006.01); C12N 5/00 (2006.01); C07K 1/00 (2006.01); C07K 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention providesGPCR (DmGPCR) polypeptides and polynucleotides which identify and encode such a DmGPCR. In addition, the invention provides expression vectors, host cells, and methods for its production. The invention also provides methods for the identification of homologs in other species and of DmGPCR agonists/antagonists useful as potential insecticides. The invention further provides methods for binding a DmGPCR, methods for identifying modulators of DmGPCR expression and activity, methods for controlling a population of insects with a DmGPCR antibody, a DmGPCR antisense polynucleotide, a DmGPCR binding partner or modulator, and methods of preventing or treating a disease or condition associated with an ectoparasite. Specifically, this invention discloses the matching of the orphandrotachykinin, droleucokinin, and drostatin-C receptors with their cognate peptide ligands.


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