The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2008

Filed:

May. 18, 2004
Applicants:

Sheng Hao Chao, San Diego, CA (US);

Jeremy S. Caldwell, Cardiff, CA (US);

Inventors:

Sheng Hao Chao, San Diego, CA (US);

Jeremy S. Caldwell, Cardiff, CA (US);

Assignee:

IRM, LLC, Hamilton, BM;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01); C12Q 1/70 (2006.01); C12P 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to the discovery that the transcription factors Pbx1 and HMG I are involved in retrovirus, e.g., HIV, replication. Thus, the invention provides methods of identifying modulators of these proteins. Such modulators can be used as reagents in in vitro assays to modulate expression of retroviral sequences and may be used to inhibit HIV replication in vivo.


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