The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 22, 2008
Filed:
Oct. 07, 2004
Peter Jan Leonard Mario Quaedflieg, Waalre, NL;
Franciscus Alphons Marie Lommen, Horst, NL;
Robert Jan Vijn, Venlo, NL;
Danniël Adrianus Franciscus Jacobus Boxtel Van, Weert, NL;
Peter Jan Leonard Mario Quaedflieg, Waalre, NL;
Franciscus Alphons Marie Lommen, Horst, NL;
Robert Jan Vijn, Venlo, NL;
Danniël Adrianus Franciscus Jacobus Boxtel Van, Weert, NL;
DSM IP Assets B.V., Heerlen, NL;
Abstract
The invention relates to a process for the preparation of (S)-glyceraldehyde acetonide in aqueous solution from 3,4-O-isopropylidene-L-threonic acid or a salt thereof in aqueous solution, and hypochlorite in aqueous solution wherein the aqueous hypochlorite solution has a pH>7.5 and wherein during addition of at least 0.1 molar equivalents of hypochlorite based on the amount of 3,4-O-isopropylidene-L-threonic acid, an acid solution is not simultaneously added. The invention also relates to a process according to the invention, wherein 3,4-O-isopropylidene-L-threonic acid or a salt thereof is prepared from 5,6-O-isopropylidene-L-ascorbic acid or a salt thereof in the presence of HOand a base in a manner known per se, wherein excess HOis optionally removed by catalase. The invention also relates to a process according to the invention, wherein 5,6-O-isopropylidene-L-ascorbic acid or a salt thereof is prepared by reacting L-ascorbic acid or a salt thereof with an acetonide forming agent, preferably in the presence of an acid catalyst.