The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 22, 2008
Filed:
May. 22, 2006
Tadamitsu Kishimoto, Tondabayashi-shi, Osaka 584, JP;
Takashi Nagasawa, Sakai, JP;
Kazunobu Tachibana, Sakai, JP;
Hisashi Iizasa, Kanazawa, JP;
Nobuaki Yoshida, Kashiba, JP;
Toshihiro Nakajima, Toyonaka, JP;
Osamu Yoshie, Nishinomiya, JP;
Tadamitsu Kishimoto, Tondabayashi-shi, Osaka 584, JP;
Takashi Nagasawa, Sakai, JP;
Kazunobu Tachibana, Sakai, JP;
Hisashi Iizasa, Kanazawa, JP;
Nobuaki Yoshida, Kashiba, JP;
Toshihiro Nakajima, Toyonaka, JP;
Osamu Yoshie, Nishinomiya, JP;
Shionogi & Co., Ltd, Osaka, JP;
Other;
Abstract
The present invention pertains to a DNA encoding a polypeptide including an entire sequence of the amino acid sequence as shown by SEQ ID NO: 2 or a partial sequence thereof, or a polypeptide including the polypeptide described above, wherein any of the polypeptides has an activity of a receptor capable of binding to a murine PBSF/SDF-1; a polypeptide encoded by the DNA described above, wherein the polypeptide has an activity of a receptor capable of binding to a murine PBSF/SDF-1; cells expressing the polypeptide described above and a human CD4 protein; and a method of screening an AIDS onset inhibitor or an HIV-1 infection inhibitor, characterized by the use of the cells described above. According to the present invention, there can be provided a novel murine CXC chemokine receptor gene, a method of screening an HIV-1 infection inhibitor, and the like, each of which is useful in studies of a therapeutic agent for AIDS and the functional mechanism of HIV-1 infection.