The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 22, 2008

Filed:

Jun. 20, 2005
Applicants:

Silvia Gatti Mcarthur, Basel, CH;

Cornelia Hertel, Muenchenstein, CH;

Matthias Heinrich Nettekoven, Grenzach-Wyhlen, DE;

Susanne Raab, Basel, CH;

Olivier Roche, Folgensbourg, FR;

Rosa Maria Rodriguez-sarmiento, Basel, CH;

Franz Schuler, Riehen, CH;

Jean-marc Plancher, Hagenthal le bas, FR;

Inventors:

Silvia Gatti McArthur, Basel, CH;

Cornelia Hertel, Muenchenstein, CH;

Matthias Heinrich Nettekoven, Grenzach-Wyhlen, DE;

Susanne Raab, Basel, CH;

Olivier Roche, Folgensbourg, FR;

Rosa Maria Rodriguez-Sarmiento, Basel, CH;

Franz Schuler, Riehen, CH;

Jean-Marc Plancher, Hagenthal le bas, FR;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/55 (2006.01); A61K 31/541 (2006.01); A61K 31/5377 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/4045 (2006.01); C07D 209/42 (2006.01); C07D 401/02 (2006.01); C07D 413/02 (2006.01); C07D 417/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds of formula I: wherein X, R, R, R, Rand Rare as defined in the description and claims, and pharmaceutically acceptable salts thereof, to the preparation of such compounds and pharmaceutical compositions containing them. The compounds are useful for the treatment and/or prevention of diseases which are associated with the modulation of H3 receptors.


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