The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 22, 2008

Filed:

Aug. 22, 2006
Applicants:

Charles Alois Dvorak, Palo Alto, CA (US);

Lawrence Emerson Fisher, Mountain View, CA (US);

Keena Lynn Green, Newark, CA (US);

Ralph New Harris, Iii, Redwood City, CA (US);

Hans Maag, Menlo Park, CA (US);

Anthony Prince, Los Altos, CA (US);

David Bruce Repke, Milpitas, CA (US);

Russell Stephen Stabler, Mountain View, CA (US);

Inventors:

Charles Alois Dvorak, Palo Alto, CA (US);

Lawrence Emerson Fisher, Mountain View, CA (US);

Keena Lynn Green, Newark, CA (US);

Ralph New Harris, III, Redwood City, CA (US);

Hans Maag, Menlo Park, CA (US);

Anthony Prince, Los Altos, CA (US);

David Bruce Repke, Milpitas, CA (US);

Russell Stephen Stabler, Mountain View, CA (US);

Assignee:

Roche Palo Alto LLC, Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/395 (2006.01); A61K 31/553 (2006.01); A61K 31/55 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to compounds which are generally muscarinic M2/M3 receptor antagonists and which are represented by Formula I: wherein X, Y, and Z are O, S or NR, and the other substituents are as defined in the specification; and prodrugs, individual isomers, racemic or non-racemic mixtures of isomers, and pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds and methods for their use as therapeutic agents.


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