The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 22, 2008
Filed:
Sep. 17, 2003
Katsuya Satoh, Gunma, JP;
Seiichi Wada, Gunma, JP;
Issay Narumi, Gunma, JP;
Masahiro Kikuchi, Gunma, JP;
Tomoo Funayama, Gunma, JP;
Yasuhiko Kobayashi, Gunma, JP;
Katsuya Satoh, Gunma, JP;
Seiichi Wada, Gunma, JP;
Issay Narumi, Gunma, JP;
Masahiro Kikuchi, Gunma, JP;
Tomoo Funayama, Gunma, JP;
Yasuhiko Kobayashi, Gunma, JP;
Japan Atomic Energy Research Institute, Kashiwa, JP;
Abstract
The present invention is directed to directly measure distribution in vivo and the frequency of generation in vivo of DNA strand breaks which induce cell death and mutations. The present inventors accomplished the present invention by providing a method for detecting a DNA strand break in a sample, which comprises a step of binding a PprA protein derived fromto a DNA strand break and a step of detecting the PprA protein which is bound to the DNA strand break; as well as by providing a kit for detecting a DNA strand break in a sample which comprises PprA proteins derived fromand a means for detecting a PprA protein which is bound to a DNA strand break.