The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 15, 2008

Filed:

Apr. 14, 2004
Applicants:

Michael C. Van Zandt, Guilford, CT (US);

Darren Whitehouse, Westbrook, CT (US);

Kerry Combs, Wallingford, CT (US);

Shaojing HU, Hamden, CT (US);

Inventors:

Michael C. Van Zandt, Guilford, CT (US);

Darren Whitehouse, Westbrook, CT (US);

Kerry Combs, Wallingford, CT (US);

Shaojing Hu, Hamden, CT (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/00 (2006.01); C07D 498/00 (2006.01); C07D 513/00 (2006.01); C07D 405/00 (2006.01); C07D 307/87 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds and pharmaceutically acceptable salts of formula (I): which are useful in the treatment of metabolic disorders related to insulin resistance or hyperglycemia. These compounds include inhibitors of protein tyrosine phosphatase (PTP-1B) that are useful in the treatment of diabetes and other PTP-1B mediated diseases, such as cancer, neurodegenerative diseases and the like. The compounds of the invention are also useful in pharmaceutical compositions and methods of treating the aforementioned conditions.


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