The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 15, 2008

Filed:

Jun. 27, 2002
Applicants:

M. Catherine Amaral, Roswell, GA (US);

Jin-long Chen, San Mateo, CA (US);

Juan C. Jaen, Burlingame, CA (US);

David N. Johnston, Didcot, GB;

Paul Rafferty, Westbourough, MA (US);

Inventors:

M. Catherine Amaral, Roswell, GA (US);

Jin-Long Chen, San Mateo, CA (US);

Juan C. Jaen, Burlingame, CA (US);

David N. Johnston, Didcot, GB;

Paul Rafferty, Westbourough, MA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/427 (2006.01); A61K 31/428 (2006.01); C07D 277/50 (2006.01); C07D 277/82 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds, compositions and methods are provided that are useful in the treatment or prevention of a condition or disorder mediated by an uncoupling protein. In particular, the compounds of the invention modulate the expression and/or activity of UCP3. The subject compositions are particularly useful in the treatment of obesity and type II diabetes, and associated diseases


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