The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 15, 2008

Filed:

Jun. 29, 2005
Applicants:

Christopher N. Farthing, London, GB;

Paul Faulder, Manchester, GB;

Alexander D. Frenkel, Buxton, GB;

Martin J. Harrison, Stockport, GB;

Xianyun Jiao, San Mateo, CA (US);

Frank Kayser, San Francisco, CA (US);

David J. Kopecky, San Francisco, CA (US);

Jinqian Liu, Palo Alto, CA (US);

Sarah E. Lively, San Carlos, CA (US);

Rajiv Sharma, Fremont, CA (US);

Stephen J. Shuttleworth, Bourne End, GB;

Inventors:

Christopher N. Farthing, London, GB;

Paul Faulder, Manchester, GB;

Alexander D. Frenkel, Buxton, GB;

Martin J. Harrison, Stockport, GB;

Xianyun Jiao, San Mateo, CA (US);

Frank Kayser, San Francisco, CA (US);

David J. Kopecky, San Francisco, CA (US);

Jinqian Liu, Palo Alto, CA (US);

Sarah E. Lively, San Carlos, CA (US);

Rajiv Sharma, Fremont, CA (US);

Stephen J. Shuttleworth, Bourne End, GB;

Assignee:

Amgen Inc., Thousands Oaks, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 413/10 (2006.01); A61P 35/04 (2006.01); C07F 9/02 (2006.01); A61K 31/519 (2006.01); A61K 31/5355 (2006.01); A61K 31/675 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds that modulate the action of ACK1 and LCK, and related compositions methods for treating ACK1- and LCK-mediated diseases are described. In one aspect, the compounds have the general structure: where the values of the substituents are provided herein.


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