The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 15, 2008
Filed:
Aug. 11, 2003
Hitoshi Murai, Osaka, JP;
Takeshi Endo, Osaka, JP;
Noriyuki Kurose, Osaka, JP;
Teruhiko Taishi, Osaka, JP;
Hiroshi Yoshida, Osaka, JP;
Hitoshi Murai, Osaka, JP;
Takeshi Endo, Osaka, JP;
Noriyuki Kurose, Osaka, JP;
Teruhiko Taishi, Osaka, JP;
Hiroshi Yoshida, Osaka, JP;
Shionogi & Co., Ltd., Osaka, JP;
Abstract
A heterocyclic compound of the formula (I): wherein Bis —C(R)═ or —N═; R' is H, etc.; one of Rand Ris -Z-Z-Z-Rwherein Zand Zare independently single bond, optionally substituted alkylene, etc.; Zis single bond, optionally substituted alkylene, etc.; Ris optionally substituted aryl, optionally substituted heteroaryl, etc., and the other of Rand Ris H; -A- is —C(—Y)═C(—R)—C(—R)═C(—R)—, etc. wherein Y is OH, etc.; Ris —CORwherein Ris OH, etc.; one of Rand Ris carboxy, etc., and the other of Rand Ris H, etc,a prodrug thereof, a pharmaceutically acceptable salt thereof, and a solvate thereof, having an antiviral activity, more particularly, an inhibitory activity against HIV integrase, and a pharmaceutical composition containing the same, especially an anti-HIV drug.