The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2008
Filed:
Jun. 28, 2005
Eugenio Castelli, Arlate di Calco, IT;
Giuseppe Lo Monaco, Seregno, IT;
Silvia Mantovani, Cesano Maderno, IT;
Paola Daverio, Villasanta, IT;
Paolo Riva, Monza, IT;
Alessandra Vailati, Seregno, IT;
Stefano Bianchi, Como, IT;
Eugenio Castelli, Arlate di Calco, IT;
Giuseppe Lo Monaco, Seregno, IT;
Silvia Mantovani, Cesano Maderno, IT;
Paola Daverio, Villasanta, IT;
Paolo Riva, Monza, IT;
Alessandra Vailati, Seregno, IT;
Stefano Bianchi, Como, IT;
Teva Pharmaceutical Fine Chemicals S.r.l., Bulciago (LC), IT;
Abstract
Provided are processes for preparing tomoxetine comprising reacting N-methyl-3-hydroxy-3-phenylpropylamine with dimethylsulfoxide (DMSO) and 2-fluorotoluene in the presence of an alkali base to form tomoxetine. Also provided is the conversion of said tomoxetine into atomoxetine or a pharmaceutically acceptable salt thereof.