The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 08, 2008

Filed:

Mar. 29, 2002
Applicants:

Tsuyoshi Yamagata, Sunto-gun, JP;

Kaoru Atsuki, Sunto-gun, JP;

Tetsuji Ohno, Sunto-gun, JP;

Shiro Shirakura, Mishima, JP;

Akira Karasawa, Sunto-gun, JP;

Inventors:

Tsuyoshi Yamagata, Sunto-gun, JP;

Kaoru Atsuki, Sunto-gun, JP;

Tetsuji Ohno, Sunto-gun, JP;

Shiro Shirakura, Mishima, JP;

Akira Karasawa, Sunto-gun, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/38 (2006.01); A61K 31/44 (2006.01); A61K 31/42 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a therapeutic agent for bladder irritative symptoms associated with benign prostatic hyperplasia comprising, as an active ingredient, a tricyclic compound represented by formula (I): [wherein Rrepresents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkoxy or halogen;X-X-Xrepresents CR═CR—CR═CR, N(O)═CR—CR═CR, CR═CR—N(O)═CR, CR═CR—CR═N(O), CR═CR—O, CR═CR—S, O—CR═CR, S—CR═CRor O—CR═N;Y represents 13 CHS—, —CHSO—, —CHSO—, —CHO—, —CH═CH—, —(CH)—, —SCH—, —SOCH—, —SOCH— or —OCH—; andRrepresents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl, substituted or unsubstituted lower alkoxy, amino, mono(substituted or unsubstituted lower alkyl)-substituted amino, di(substituted or unsubstituted lower alkyl)-substituted amino, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted aralkylamino, substituted or unsubstituted arylamino or a substituted or unsubstituted heteroalicyclic group] or a pharmaceutically acceptable salt thereof.


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