The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 08, 2008

Filed:

Dec. 03, 2004
Applicants:

Takashi Hayama, Tsukuba, JP;

Kyoko Hayashi, Tsukuba, JP;

Teruki Honma, Tsukuba, JP;

Ikuko Takahashi, Tsukuba, JP;

Inventors:

Takashi Hayama, Tsukuba, JP;

Kyoko Hayashi, Tsukuba, JP;

Teruki Honma, Tsukuba, JP;

Ikuko Takahashi, Tsukuba, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); C07D 405/12 (2006.01); A61K 31/423 (2006.01); A61K 31/424 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a compound of Formula (I) and the manufacturing method(s) thereof and the use thereof: Formula (I) wherein: Ar is a nitrogen-containing heteroaromatic ring group; X and Z are each a carbon atom, and so on; Y is CO, and so on; Ris a hydrogen atom, and so on; Rand Rare each a hydrogen atom, and so on; Rand Rare each a hydrogen atom, and so on; and the formulais a single bond or a double bond. According to the present invention, the compound of the present invention can provide Cdk4 and/or Cdk6 inhibitors for treating malignant tumors, because the compounds of the present invention exhibit a prominent growth inhibitory activity against tumor cells.


Find Patent Forward Citations

Loading…