The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2008
Filed:
Jun. 06, 2003
Gary Bridger, Bellingham, WA (US);
AL Kaller, Vancouver, CA;
Curtis Harwig, Vancouver, CA;
Renato Skerlj, Vancouver, CA;
David Bogucki, Surrey, CA;
Trevor R. Wilson, Langley, CA;
Jason Crawford, Vancouver, CA;
Ernest J. Mceachern, White Rock, CA;
Bem Atsma, Abbotsford, CA;
Siqiao Nan, Richmond, CA;
Yuanxi Zhou, Surrey, CA;
Dominique Schols, Herent, BE;
Christopher Dennis Smith, Toronto, CA;
Maria Rosaria Di Fluri, Burnaby, CA;
Gary Bridger, Bellingham, WA (US);
Al Kaller, Vancouver, CA;
Curtis Harwig, Vancouver, CA;
Renato Skerlj, Vancouver, CA;
David Bogucki, Surrey, CA;
Trevor R. Wilson, Langley, CA;
Jason Crawford, Vancouver, CA;
Ernest J. McEachern, White Rock, CA;
Bem Atsma, Abbotsford, CA;
Siqiao Nan, Richmond, CA;
Yuanxi Zhou, Surrey, CA;
Dominique Schols, Herent, BE;
Christopher Dennis Smith, Toronto, CA;
Maria Rosaria Di Fluri, Burnaby, CA;
Anormed, Inc., Langley, British Columbia, CA;
Abstract
The invention relates to heterocyclic compounds consisting of a core nitrogen atom surrounded by three pendant groups, wherein two of the three pendant groups are preferably benzimidazolyl methyl and tetrahydroquinolyl, and the third pendant group contains N and optionally contains additional rings. The compounds bind to chemokine receptors, including CXCR4 and CCR5, and demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).