The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2008
Filed:
Nov. 29, 2004
Applicant:
Richard E. Olson, Wilmington, DE (US);
Inventor:
Richard E. Olson, Wilmington, DE (US);
Assignee:
Bristol-Myers Squibb Pharma Company, Princeton, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 267/02 (2006.01); C07D 281/02 (2006.01); C07D 291/02 (2006.01); A61K 31/55 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention relates to novel lactams having the Formula (I): to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifically, inhibit the production of Aβ-peptide, thereby acting to prevent the formation of neurological deposits of amyloid protein. More particularly, the present invention relates to the treatment of neurological disorders related to β-amyloid production such as Alzheimer's disease and Down's Syndrome.